Duspatalin 100

Duspatalin indications

Irritable bowel syndrome & allied conditions eg, chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Symptomatic treatment of abdominal pain, cramps, nonspecific diarrhoea & flatulence. GI spasm secondary to organic diseases eg, diverticulitis, gastritis, duodenitis, oesophagitis, cholecystitis, Crohn’s disease, ulcerative colitis, peptic ulcer, gallbladder disease, hiatus hernia, GIT inflammation.

Uses of Duspatalin in details

Duspatalin is used to treat irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits). It is also used to treat other conditions that involve spasm and pain related to small and large bowel.

Duspatalin description

Each capsule contains Mebeverine 100 mg.
Duspatalin also contains the following excipients: Capsule Content (Granules): Magnesium stearate, polyacrylate dispersion 30%, talc, hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30% and glycerol triacetate. Capsule Shell: Gelatin, titanium dioxide (E171). Printing Ink: Shellac (E904), black iron oxide (E172), propylene glycol, concentrated ammonia solution, potassium hydroxide.

Duspatalin dosage

Adults: 1 capsule twice daily (1 in the morning and 1 in the evening).

Special Populations: Elderly, Renal and Hepatic Impairment: No posology studies in elderly, renal and/or hepatically impaired patients have been performed. However, no specific risk for elderly, renal and/or hepatically impaired patients could be identified from available post-marketing data. No dosage adjustment is deemed necessary in these patients.

Missed Dose: In case of ≥1 doses missed, continue with the next dose as prescribed; the missed doses are not to be taken in addition to the regular dose.

Administration: The capsules should be swallowed with a sufficient amount of water (at least 100 mL of water).

It should not be chewed because the coating is intended to ensure a prolonged release mechanism.

Duspatalin interactions

No interaction studies have been performed except with alcohol. In vitro and in vivo studies in animals have demonstrated the absence of any interaction between Duspatalin and ethanol.

Incompatibilities: Not applicable.

Duspatalin side effects

Although adverse effects appear rare, gastrointestinal disturbances, dizziness, headache, insomnia, anorexia and tachycardia have been reported in patients receiving Duspatalin.

Duspatalin contraindications

Hypersensitivity to Duspatalin HCl or to any of the excipients of Duspatalin.