Tadasoft-40

Sunrise’s Tadasoft-40 is made with the intention of providing a quicker onset of action compared to standard Tadalafil pills. It is presented in a soft chewable form, wich leads to quick absorption. The drug reaches its target faster than the onset of action observed on taking a pill. Hence onset of action using Tadasoft-40 can be seen in about 15 minutes in comparison to about 1 hour to 90 minutes when taking Cialis or Pfizer’s Tadalift pills. This allows having spontaneous sexual activity without waiting for a long duration for the drug to work.

HOW IT WORKS

To get to know about the method in which Tadasoft-40 (Tadalafil, 40mg) tabs do their work, you should know about the mechanism of erections.

Upon sexual arousal, there is the transmission of signals between the brain and the structure of the penis. This causes release of certain chemicals and enzymes that cause smooth muscles contained in the penis to relax. Under normal circumstances, these smooth muscles remain constricted and blood flow is limited. Upon relaxation of these muscles, more blood is able to get into the penis resulting in an erection.

The erection is lost when an enzyme called PDE5 (phosphodiesterase type5) is released which causes the reversal of the process by causing the breakdown of certain enzymes released during sexual arousal and erection. This reversal brings the smooth muscles to its original constricted state causing the exit of blood from the penis and loss of erection.

Tadalafil is an inhibitor of PDE5. By inhibiting the actions of PDE5, the breakdown of the enzymes responsible for erection is inhibited thereby allowing the erection to remain intact for a longer duration of time. As the erection remains longer, the person is able to undertake sexual activity and intercourse.

HOW TO USE

Tadasoft-40 is a medication that is available on prescription as is used in the management of erectile dysfunction. This is a condition seen in men who experience an inability to obtain an erection or have a problem with maintaining the erection to enable successful sexual intercourse. The person is diagnosed to have erectile dysfunction if he is experiencing the problem on a regular basis and not on a one-off basis.

DOSAGE

The initial dose that anyone starts off with is 10mg prior to sexual activity. If the therapeutic results are not very effective, then the dose is adjusted to 20 mg once a day prior to sexual activity. It is not advisable to take Tadasoft-40 along with other medications to treat erectile dysfunction like Sildenafil citrate (Viagra).

CONTRAINDICATIONS

Before beginning to take Tadasoft-40, it is advisable to seek advice and assessment from a medical professional especially if you are suffering from any of the following conditions:

Allergies to any constituents of the medication
Any cardiovascular problems such as congestive cardiac failure, angina or arrhythmias.
Liver disorders including liver failure
Kidney disorders including renal failure
An eye disorder such as retinitis pigmentosa
Ulcers in the GI tract
Recent history of a stroke, arrhythmia or a heart attack
Severe disturbances of vision that also includes some conditions like NAION
Bleeding disorders
Leukemia
Multiple myeloma
Sickle cell anemia
Hypertension
Hypotension
Priapism, a condition in which the person experiences painful and prolonged erections for period more than 6 hours
Penile deformations like Peyronie’s disease, angulation and cavernosal fibrosis.

SIDE EFFECTS

There have been widespread clinical studies and trials for evaluating Tadasoft-40 in which more than 5700 people have participated. The adverse effects of the drug have been carefully studied. The results of the studies have shown that the more common adverse effects are seen in about 2% of people and these side effects include:

Headache is seen in about 15% of people
Dyspepsia or Indigestion occurs in about 10% of people
Back Pain is known to happen in about 6% of persons
Myalgia (muscular pain) is known to occur in about 4% of people
Facial Flushing is seen to occur in around 3% of people
Nasal Congestion is seen in around 3% of persons taking Tadalafil
Pain occurring in the legs and arms are seen in about 3% of people taking the drug.

The clinical trials also established certain other adverse effects in about 2% of persons taking Tadasoft-40. Some of these adverse effects that were observed include the following:

Dryness of the mouth
Vertigo (feeling of reeling)
Hypertension or high BP
Insomnia or sleeplessness
Angina
Migraine headache
Hearing disturbances including hearing loss
Blurring of the vision and vision disturbances
Unexplained skin rashes
Priapism with painful and prolonged erections lasting for a period beyond 6 hours.

DRUG INTERACTIONS

Tadalafil can lead to some drug interactions when taken concomitantly with some other medications. So, the use of Tadalafil may not be advisable or should be with caution if the person is taking some other medications such as:

Antihypertensive medications
Theophylline
The use of alpha blockers to counter hypertension or for the management of benign hyperplasia of the prostate.
CYP 3A4 inhibiting drugs
Some other type of erectile dysfunction medications such as Sildenafil citrate or Vardenafil (PDE5 inhibitors).